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Richter's syndrome; Richter transformation
Chronic lymphocytic leukemia that has transformed into diffuse large cell lymphoma.
Clinical manifestations:
1) fever
2) massive asymmetric adenopathy
3) splenomegaly
Management: Prognosis: poor
Related
chronic lymphocytic leukemia (CLL)
diffuse large B-cell lymphoma (DLBCL)
General
syndrome
References
Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed)
Lippincott-Raven, Philadelphia, 1998, pg 421